National manufacturer of
immunobiological products in Russia
En
National manufacturer of
immunobiological products in Russia
History of the Branch

The Regional Sanitary and Bacteriological Institute was based on the Province Sanitary and Bacteriological Station, the Province Pasteur Station and the Province Malaria Station in 1929. In 1933, it was transformed into the Regional Institute of Epidemiology and Microbiology. In 1940, the institute was expanded by the production department for vaccines, serums and other immunobiological preparations. In 1960, the RF Ministry of Health ordered to establish a company on the basis of the department as part of the Gorky Scientific and Research Institute of Epidemiology and Microbiology.

In 1992, an independent legal entity – the Nizhny Novgorod Enterprise of Bacterial Preparation “ImBio” – was separated from the institute and subordinated to the Ministry of Health of the Russian Federation.

On June 16, 2003, the company was reorganized into the Branch of FSUE NPO Microgen of the Russian Ministry of Health “Nizhny Novgorod Enterprise of Bacterial Preparation “ImBio”.

Among preparations produced by the Branch the leading place belongs to immunoglobulins and blood products, such as human normal immunoglobulin for intravenous administration, specific immunoglobulins, a complex immunoglobulin preparation for oral administration (CIP), albumin, ceruloplasmin. In early 70s of the last century, the company started production of the country’s first specific antistaphylococcal immunoglobulin. Some employees of the institute and the gamma globulin shop were awarded the State Prize for the development of the immunoglobulin.

A significant group in the Branch’s range of products is bacteriophages. The bacteriophage shop is the country’s larges production unit, which started operations in 1941 with the production of bacteriophages against dysentery, which was a high prevalence disease during the war. Currently, the Nizhny Novgorod branch has the widest range of bacteriophage of all Russian producers.

A significant share in the production volume also belongs to probiotics – bifidumbakterin, lactobacterin, colibacterin in various dosage forms. The Nizhny Novgorod enterprise was the first in the country to start the production of dry bifidumbakterin and probiotic tablets in 1975. In 1978, bifidumbakterin tablets were used in aerospace medicine and in 1984 the preparation was awarded the Silver Medal in the All-Russian Exhibition Center. From 1998 to 2000, the company launched new dosage forms of probiotics in suppositories and the complex preparation – bificol.

In early 70s of the last century, the production of diagnostic systems was separated in a new area. Currently, the range of produced diagnostic preparations is represented by monospecific serums, paper indicator systems, immunoassay systems. The latest development of the shop’s specialists is the immunoassay system for quantitative assay of НВsAg antibodies (MicrAT-НВs) produced according to a unique technology since 2010.

The Nizhny Novgorod branch has its own scientific and research base and carries out applied scientific researches for the development and improvement of drugs and related production technologies. The main results of the company’s scientific and production activities are protected by patents and copyrights.