Description
The vaccine is surface glycoproteins (hemagglutinin and neuraminidase) isolated from purified virions of influenza virus types A and B obtained from the virus-containing allantoic fluid from chick embryos of clinically healthy chickens and diluted in phosphate-buffered saline in combination with adjuvant SOVIDON TM. The drug is available with the preservative thiomersal (merthiolate) or without a preservative. <br>
The antigenic structure of the strains is varied each year according to guidelines of the WHO and the Commission on Influenza Vaccines and diagnostic strains of the Russian Ministry of Health.
Presentation
solution for intramuscular injection, 0.5 ml (1 dose) per ampule or disposable syringes with needles and protective caps. 10 ampoules in each cardboard box with a package insert and an ampoule cutter. 5 ampoules in each dose tray. 2 PVC blister in each cardboard package with a package insert and an ampoule cutter. If the ampoule has a score line, a ring or a dot, an ampoule cutter is not inserted. 1 syringe in each PVC blister. 1 PVC blister in each cardboard package with a package insert.
Ingredients
1 dose (0.5 ml) contains:
Vaccine with preservative
- hemagglutinin of influenza virus subtype A(H1N1) - 5 µg;
- hemagglutinin of influenza virus subtype А(H3N2) - 5 µg;
- hemagglutinin of influenza virus type B - 11 µg;
- SOVIDON adjuvant - 500 µg;
- preservative – thiomersal (merthiolate) - (50.0 ± 7.5) µg;
- phosphate buffered saline - up to 0.5 ml.
Vaccine without preservative
- hemagglutinin of influenza virus subtype A(H1N1) - 5 µg;
- hemagglutinin of influenza virus subtype А(H3N2) - 5 µg;
- hemagglutinin of influenza virus type B - 11 µg;
- SOVIDON adjuvant - 500 µg;
- phosphate buffered saline - up to 0.5 ml.
Note.
Composition of phosphate buffered saline #1 (for the preparation without preservative): 9 g of sodium chloride, 1.5 g of sodium hydrogen phosphate, 0,12-0,14 g of potassium dihydrogen, water for injection up to 1 liter.
Composition of phosphate buffered saline #2 (for the preparation with preservative): 9 g of sodium chloride, 1.5 g of sodium hydrogen phosphate, 0,12-0,14 g of potassium dihydrogen, 0.85 ml of 1% thiomersal (merthiolate) solution, water for injection up to 1 liter.
Description. Colorless or yellowish transparent liquid.
Immunobiological properties. The vaccine develops high specific immunity against seasonal flu.
Indications
Active annual preventive immunization against seasonal influenza in people aged 18 and above
The vaccine is particularly indicated
1. To persons with high risk of disease or complications if infected with influenza:
- people over 60 years old;
- people with frequent episodes of acute respiratory viral infections
- people with chronic medical conditions, including diseases and malformations of the cardiovascular, respiratory and central nervous system, chronic kidney diseases, metabolic diseases, diabetes, chronic anemia, allergic diseases (except allergy to chicken proteins); congenital or acquired immunodeficiency, including infected with human immunodeficiency virus.
2. People who due to their educational or professional activities have a high risk of catching influenza or infecting other people;
- students over 18 years old;
- healthcare workers;
- workers of the social, management, education, service, catering, transportation, trade spheres;
- military men, policemen.
